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用放射免疫分析测定了脑血管病病人血清TNF－α值，结果显示脑出血、脑梗塞病人血清TNF－α值分别为20．10±8．64和22．58±10．17pmol／L，均显著高于参照血清TNF－α（P＜0．01）。对6例脑出血病人、2例蛛网膜下腔出血病人分别在住院当日及以后测血清TNF－α值，结果显示治疗后血清TNF－α值明显下降。结果提示，TNF－α对脑血管病的发生、发展有影响。
The level of serum TNF-α in patients with cerebrovascular disease was measured by radioimmunoassay. The results showed that the serum levels of TNF-α in patients with cerebral hemorrhage and cerebral infarction were 20.10 ± 8.64 and 22.58 ± 10.17pmol / L, respectively Significantly higher than the reference serum TNF-α (P <0.01). Serum TNF-α was measured in 6 patients with cerebral hemorrhage and 2 patients with subarachnoid hemorrhage on the day of hospitalization and later, respectively. The results showed that serum TNF-α decreased significantly after treatment. The results suggest that TNF-α has an impact on the occurrence and development of cerebrovascular disease.