对７２例慢性阻塞性肺病（ＣＯＰＤ）铜绿假单胞菌感染（ＰＡ）、医院支气管肺感染（ＮＢＰＩ）的患者行痰ＰＡ血清学、噬菌体及绿脓菌素分型并做药敏试验。结果示本组ＰＡ以血清型４型为主，其绿脓菌素型为４２５３３４，依药敏选抗生素，均获良好症状控制，但仅２５％痰ＰＡ持续阴性，余反复阳性。提示ＰＡ所致ＣＯＰＤ患者ＮＢＰＩ治疗目的为控制急性症，常不能根除ＰＡ，但可有效防止新的医院感染发生。 72 patients with chronic obstructive pulmonary disease (COPD) of Pseudomonas aeruginosa infection (PA), hospital bronchial pneumonia (NBPI) patients sputum PA serology, phage and pyocyanin typing and drug susceptibility testing. The results showed that this group of PA serotype 4-based, pyocyanin-type 425,334, according to drug-sensitive antibiotics, were controlled by good symptoms, but only 25% sputum PA persistent negative, I repeatedly positive. It is suggested that the purpose of NBPI treatment in patients with PA caused by PA is to control acute illness and often can not eradicate PA, but can effectively prevent the occurrence of new nosocomial infections.