当处于发育抑制阶段的感染性钩虫幼虫 (L3)进入终宿主后 ,会遇到一种启动其暂停发育路径的宿主特异性的信号。宿主信号的转导启动影响寄生状态十分必要的一系列寄生虫编码基因的表达 ,并且导致L3发生形态和发育上的重大变化。对此转变过程中发生的分子事件目前了解很少 ,原因主 When infective hookworm larvae (L3) in the stage of developmental depression enter the final host, they encounter a host-specific signal that initiates their pause in developmental pathways. The transduction of the host signal initiates the expression of a series of parasite-encoding genes that affect parasitism and causes significant morphological and developmental changes in L3. There is very little understanding of the molecular events that have taken place in this transition, mainly because of the main reason