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目的分析全静脉营养干预与传统营养干预在新生儿营养改善方面的临床效果,探讨营养干预对低体重新生儿营养状态和生化指标的影响。方法选取2014年6月-2015年2月分娩并因低体重于儿科进行治疗的新生儿80例,随机分为两组,采用全静脉营养干预的40例新生儿为观察组,采用传统营养干预的其余40例新生儿为对照组,比较两组新生儿的营养干预效果。应用SPSS 19.0统计软件统计分析所得数据,P<0.05为差异有统计学意义。结果经过干预治疗后,观察组和对照组新生儿体重分别为(1.9±0.2)kg和(1.7±0.1)kg,身长分别为(46.7±2.8)cm和(44.6±2.7)cm,上臂围分别为(9.4±0.5)cm和(7.8±0.4)cm,观察组新生儿体重、身长及上臂围的改善幅度明显优于对照组,差异均具有统计学意义(P<0.05)。经过干预治疗后,观察组和对照组新生儿的血清前蛋白水平分别为(69.0±6.0)mg/L和(84.0±7.0)mg/L,血清胆红素水平分别为(121.0±11.0)mmol/L和(156.0±12.0)mmol/L,血清尿素氮水平分别为(5.0±1.4)mmol/L和(5.8±1.6)mmol/L,观察组新生儿血清前蛋白、胆红素及尿素氮水平改善程度均优于对照组,差异均具有统计学意义(P<0.05)。观察组和对照组红细胞C3b受体花环率(RBC-C3bRR)分别为(13.0±2.0)%和(11.0±2.0)%,红细胞免疫抑制率(FEIR)分别为(13.0±2.0)%和(14.0±2.0)%,红细胞免疫促进因子(FEER)分别为(86.0±5.0)%和(84.0±5.0)%,观察组新生儿上述生化指标水平基本恢复正常,改善效果更明显,与对照组新生儿比较,差异均具有统计学意义(P<0.05)。结论因对低体重新生儿采用全静脉营养干预的方式可不同程度地改善其生长、免疫和身体各项机能的成熟,临床上效果明显,可推广使用。
Objective To analyze the clinical effect of total parenteral nutrition intervention and traditional nutrition intervention on the improvement of neonatal nutrition, and to explore the effect of nutrition intervention on nutritional status and biochemical indexes of low birth weight neonates. Methods Eighty newborn babies who gave birth and were treated with low birth weight in pediatrics from June 2014 to February 2015 were randomly divided into two groups. Forty newborn infants with total parenteral nutrition intervention were used as the observation group. The traditional nutritional intervention The remaining 40 newborns as a control group, the two groups of newborns nutrition intervention effect. SPSS 19.0 statistical software statistical analysis of the data, P <0.05 for the difference was statistically significant. Results After intervention, the newborn infants in the observation group and the control group were (1.9 ± 0.2) kg and (1.7 ± 0.1) kg in weight, respectively (46.7 ± 2.8) cm and (44.6 ± 2.7) cm in height, respectively (9.4 ± 0.5) cm and (7.8 ± 0.4) cm respectively. The weight, body length and upper arm circumference of newborns in observation group were significantly better than those in control group (P <0.05). After intervention, the levels of serum prolactin in observation group and control group were (69.0 ± 6.0) mg / L and (84.0 ± 7.0) mg / L respectively, and the serum bilirubin levels were (121.0 ± 11.0) mmol / L and (156.0 ± 12.0) mmol / L respectively, and serum urea nitrogen levels were (5.0 ± 1.4) mmol / L and (5.8 ± 1.6) mmol / L respectively in the observation group. Serum pre-protein, bilirubin and urea nitrogen The level of improvement was better than the control group, the differences were statistically significant (P <0.05). The erythrocyte C3b receptor rosette rate (RBC-C3bRR) was (13.0 ± 2.0)% and (11.0 ± 2.0)% respectively in the observation group and the control group, and the erythrocyte immunosuppression rates (FEIR) were (13.0 ± 2.0)% and ± 2.0%, and FEER were (86.0 ± 5.0)% and (84.0 ± 5.0)%, respectively. The biochemical indexes in the newborns of the observation group returned to normal and the improvement effect was more obvious. Compared with the neonatal The differences were statistically significant (P <0.05). Conclusion The method of total parenteral nutrition intervention in low birth weight infants can improve the growth, immunity and maturation of various functions of the body in varying degrees. The clinical effect is obvious and can be used widely.