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本文采用放射免疫法及放射受体法分别测定了14名健康人及26名肥胖型NIDDM患者血浆胰岛素、C-肽及全血细胞胰岛素受体（INSR）。结果显示NIDDM患者血浆胰岛素及C-肽水平均显著高于健康人（P＜0．05），而胰岛素受体数目显著减少（P＜0．01）。提示肥胖型NID－DM存在胰岛素受体缺陷，巨以数量少而高亲和力的功能性受体为主要标志。
In this study, plasma insulin, C-peptide and whole blood insulin receptor (INSR) were measured in 14 healthy individuals and 26 obese NIDDM patients by radioimmunoassay and radioimmunoassay. The results showed that the levels of plasma insulin and C-peptide in patients with NIDDM were significantly higher than those in healthy people (P <0.05), while the number of insulin receptors was significantly decreased (P <0.01). Tip obese NID-DM has insulin receptor deficiencies, with a large number of high-affinity functional receptors as the main sign.