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间日疟地理分布广,是现今疟疾控制和消除的最大挑战之一。本文通过查阅各类相关数据库,综述了间日疟控制和消除的挑战及其应对策略研究进展。各类来源的研究资料显示间日疟更易于传播,媒介控制措施效果差;无症状和亚显微镜检测密度带虫者比例高,常规检测困难;磷酸伯氨喹啉(唯一根治药)安全性低。为应对这些挑战,现正在从传播阻断、实验诊断、抗疟药物和方案等方面开展研究。
The widespread distribution of vitex malaria is one of the greatest challenges in the control and elimination of malaria today. This article reviews all kinds of related databases, summarizes the research progress of control and elimination of vivax malaria and its coping strategies. Research data from various sources show that Vivax malaria is more likely to spread and media control measures ineffective; asymptomatic and sub-microscopic density densities are associated with high rates of insects, routine testing is difficult; and primaquine phosphate (the only cure) is less safe . To address these challenges, research is being carried out in the fields of transmission blockage, laboratory diagnosis, anti-malarial drugs and programs.