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目的探讨结节性甲状腺肿合并甲状腺癌的诊断方法及治疗的可行性。方法回顾性分析120例手术确诊的甲状腺肿并发甲状腺癌患者的临床资料。结果彩超及冰冻切片病理诊断的符合率分别为55.8%和94.2%,差异具有统计学意义(P<0.05)。手术治疗后无一例患者死亡,经6~48个月随访,无一例患者出现甲状腺癌转移和复发。结论结节性甲状腺肿并甲状腺癌应用超声诊断有一定的临床指导意义,但由于部分结节患者超声表现不具有典型性,因此诊断符合率有所下降;冰冻切片快速诊断具有重要意义,符合率高。在诊断早期采取有效的手术治疗方式,效果确切,提高了患者生存率。
Objective To investigate the diagnosis and treatment of nodular goiter complicated with thyroid cancer. Methods The clinical data of 120 surgically diagnosed goiter and thyroid cancer patients were retrospectively analyzed. Results The coincidence rates of color Doppler ultrasonography and frozen section pathological diagnosis were 55.8% and 94.2% respectively, the difference was statistically significant (P <0.05). None of the patients died after surgery. After 6 to 48 months of follow-up, none of the patients had thyroid cancer metastasis and recurrence. Conclusion Ultrasound diagnosis of nodular goiter and thyroid cancer has some clinical significance. However, the diagnostic coincidence rate of nodular goiter has some clinical significance because of the non-typical sonographic features of some nodules. The rapid diagnosis of frozen section is of great significance, and the coincidence rate high. In the early diagnosis and effective surgical treatment, the exact effect, improve patient survival.