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本院自1970~1979年共收治各种类型不同部位的骨髓炎388例,伴经久不愈窦道反复流脓诱发鳞状细胞癌变有4例,其发生率为1.18%,均为男性,发病年龄均在50岁以上。发生部位:股骨3例,胫骨1例。窦口反复流脓均超过30年,分泌物均具恶臭。慢性皮肤溃疡经久不愈诱发癌变者6例,男3例女3例。发病年龄38~55岁。病程:10年以上2例,5年以上2例,1年以上2例。发生部位:小腿中下段4例,其中3例伴有下肢静脉曲张,大腿下段1例,足底跟骨部1例。局部表现:创面肉芽凹凸不平易出血,有3例呈菜花样外翻,周围皮肤呈暗紫色,伴有静脉曲张的呈紫黑色,表面分泌物均具恶臭。本组10例均经病理检查证实为鳞状细胞癌,区域
In our hospital from 1970 to 1979, a total of 388 cases of various types of osteomyelitis were treated, and 4 cases of squamous cell carcinoma induced by persistent sinus recurrent pus. The incidence rate was 1.18%. All cases were male. The age is above 50 years old. Occurrence site: 3 cases of femur, 1 case of humerus. The sinus ostia was repeatedly pused for more than 30 years and the secretions were odorless. Chronic ulceration of the skin caused by chronic ulceration in 6 cases, 3 males and 3 females. The age of onset is 38 to 55 years old. Course of disease: 2 cases over 10 years, 2 cases over 5 years, and 2 cases over 1 year. Occurrence site: 4 cases of middle and lower legs, 3 of which were associated with varicose veins of the lower extremities, 1 case of the lower leg, and 1 case of the calcaneus of the plantar. Local manifestations: The granulation of the wound surface was uneven and bleeding was uneven. There were 3 cases of cauliflower eversion, the surrounding skin was dark purple, and the varicose veins were purple-black. The surface secretions were all odor. 10 cases of this group were confirmed by pathological examination as squamous cell carcinoma, regional