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目的 探讨早产儿视网膜病 (ROP)发生的相关危险因素。 方法 以 13 5例早产儿患儿为研究对象 ,对胎龄、性别、出生体重、吸氧时间、吸氧浓度、肺透明膜病、Apgar评分、颅内出血、支气管肺发育不良、反复呼吸暂停、动脉导管开放、眼底等进行检查。同时用单因素 χ2 检验和多因素logistic回归分析筛选和判定早产儿ROP发生的危险因素。 结果 13 5例中有 2 8例合并ROP ,占2 0 .7% (2 8/ 13 5)。经logistic回归分析 ,发现吸氧浓度、吸氧时间、出生体重、胎龄与早产儿ROP的发生有显著相关性 (r =0 .451,P <0 .0 5)。 结论 吸氧浓度、吸氧时间、出生体重、胎龄为早产儿ROP发生的重要危险因素 ,建议对所有早产儿常规行眼底检查 ,重视并针对其危险因素加以预防
Objective To explore the related risk factors of retinopathy of prematurity (ROP). Methods Totally 135 children with preterm infants were studied. The effects of gestational age, gender, birth weight, oxygen inhalation time, oxygen concentration, hyaline membrane disease, Apgar score, intracranial hemorrhage, bronchopulmonary dysplasia, Artery catheter open, fundus and other inspection. At the same time, single factor χ2 test and multivariate logistic regression analysis were used to screen and determine the risk factors of ROP in premature infants. Results Of 135 cases, 28 cases had ROP, accounting for 20.7% (28/135). Logistic regression analysis showed that oxygen concentration, oxygen inhalation time, birth weight and gestational age were significantly correlated with the occurrence of ROP (r = 0.451, P <0.05). Conclusion The oxygen concentration, oxygen inhalation time, birth weight and gestational age are important risk factors for ROP in preterm infants. It is suggested that all preterm infants should be routinely examined with fundus examination and attention should be given to their risk factors.