传统化学仍是获得单一对映体的主要方法,传统化学也可能达到对映体纯产品的目标,例如结晶动力学拆分制备(R)-氟比洛芬,哌啶诱导构型转换制备L-核糖。手性源和拆分方法仍多于催化不对称合成,而催化不对称合成化学的核心是催化剂的选择,不对称环氧化在工业上取得了巨大成功。 Traditional chemistry is still the main method to obtain a single enantiomer. Conventional chemistry may also achieve the goal of enantiomerically pure products, such as crystalline kinetic resolution preparation of (R) -flurbiprofen, piperidine-induced configurational conversion to prepare L - Ribose. Chiral source and resolution methods are still more than the catalytic asymmetric synthesis, and catalytic asymmetric synthesis of the core of the catalyst is the choice of catalyst, asymmetric epoxidation has achieved great success in the industry.