卵巢恶性卵黄囊瘤(又名内胚窦瘤),是一种由胚外结构——卵黄囊发生的高度恶性的生殖细胞肿瘤。本病比较少见,好发于青少年女性,病情发展迅速,治疗效果不佳。我院自1971年9月～1982年8月底共收治12例。现对上述病例之临床和病理作一回顾性分析,并结合文献复习,对有关问题予以简要的讨论。 Ovarian malignant yolk sac tumor (also known as endodermal sinus tumor), is a highly malignant germ cell tumor arising from the extra-sac structure - the yolk sac. The disease is relatively rare, occurs in young women, the rapid development of the disease, the treatment effect is not good. Our hospital since September 1971 ~ August 1982 were treated 12 cases. Now on the clinical and pathological retrospective analysis of the cases, combined with the literature review, the issues to be briefly discussed.