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手足口病是由多种肠道病毒引起的常见传染病,以婴幼儿发病为主,大多数症状较轻微,以发热和手、足、口腔等部位的皮疹或疱疹为主要特征,少数患儿可并发无菌性脑膜炎、脑炎、急性弛缓性麻痹、呼吸道感染和心肌炎等,个别重症患儿病情进展快,易发生死亡。近年来,EV71病毒的流行在亚太地区呈上升趋势,1997年马来西亚大流行感染2 628人,死亡30多人;1998年,台湾地区暴发EV71的大流行,约有12万以上的人被感染,死亡78人[1],
Hand, foot and mouth disease is caused by a variety of enterovirus common infectious diseases, mainly in infants and young children, most of the symptoms are mild to fever and hand, foot, mouth and other parts of the rash or herpes as the main features of a small number of children May be complicated by aseptic meningitis, encephalitis, acute flaccid paralysis, respiratory tract infections and myocarditis, the rapid progress of individual cases of severe illness, prone to death. In recent years, the prevalence of EV71 virus has been on the rise in the Asia-Pacific region. In 1997, a total of 2,628 people were infected with the Malaysian pandemic and more than 30 people died. In 1998, about 121,000 people were infected with the EV71 outbreak in Taiwan, 78 people died [1],