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目的:了解丽水市学龄前儿童乙型肝炎病毒(HBV)感染情况和免疫水平,为防治工作提供依据。方法:用ELISA法,对15所幼儿园的3 743名在园儿童HBV血清学标志物(HBVM)检测结果进行统计分析。结果:共检出HBsAg阳性15例,总阳性率为0.40%,其中大三阳(HBsAg、HBeAg、抗-HBc同时阳性)9例,小三阳(HBsAg、抗-HBe、抗-HBc同时阳性)1例;男、女童HBsAg阳性检出率无差异;城郊儿童HBsAg阳性检出率高于城区,差异有显著性。共检出抗-HBs阳性1 736例,总阳性率为46.38%,抗-HBs阳性检出率随年龄增长而下降。结论:丽水市学龄前儿童的HBV感染得到有效控制,乙肝防控工作取得明显成效。
Objective: To understand the status of hepatitis B virus (HBV) infection and immunization in preschool children in Lishui City, and to provide basis for prevention and treatment. Methods: The results of 3 743 HBVM test in children in 15 kindergartens were analyzed by ELISA. Results: 15 cases were positive for HBsAg, the total positive rate was 0.40%. There were 9 cases of HBeAg positive (HBsAg, HBeAg and anti-HBc positive), 9 cases positive of HBsAg (anti-HBe and anti-HBc) 1 case; male and female HBsAg positive detection rate was no difference; suburban children HBsAg positive detection rate was higher than the city, the difference was significant. A total of 1 736 anti-HBs positive cases were detected, with a total positive rate of 46.38%. The positive detection rate of anti-HBs decreased with age. Conclusion: HBV infection in pre-school children in Lishui City has been effectively controlled and the prevention and control of hepatitis B achieved remarkable results.