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Gupta和Snow注意到有些昆虫学参数(如感染叮咬率)在现场评价恶性疟原虫感染方面有一定局限性。然而,他们所提出的替代指标——婴幼儿阳转率(血涂片阳性和IgM抗体阳性作为感染的证据)似乎和叮咬率一样不准确。用一岁以下婴儿血涂片阴性到阳性的阳转率来评估社区的感染度,可能会明显低估感染的水平,进一步会低估基本繁殖率(Ro)的数值。对于无症状感染者,检测血清抗疟原虫IgM抗体方法的敏感性要比显
Gupta and Snow noted that some entomological parameters (such as the rate of infection bites) have some limitations in on-field evaluation of Plasmodium falciparum infection. However, the surrogate measures they proposed - infant positive rates (smear positive and IgM positive as evidence of infection) appear to be as inaccurate as the bite rate. Assessing the extent of infection in communities with negative-to-positive rates of conversion of baby smears at one year of age may significantly underestimate the level of infection and further underestimate the value of the basic reproductive rate (Ro). For asymptomatic infections, the detection of serum anti-Plasmodium IgM antibody sensitivity than the significant