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目的 评价燃煤型慢性砷中毒患者的神经系统损害。方法 随机检测 5 1例患者的肌电图 ,运动神经传导速度 (MCV) ,感觉神经传导速度 (SCV) ,F波 ,H反射 ,体感诱发电位 (SEP)。结果 12 0块肌肉肌电图6 6 .7%以多相不规则波为主 ;MCV与 SCV均有减慢 ,以 SCV减慢最为显著 ,而 MCV远端动作电位潜伏期明显延长 ,神经传导速度 (NCV )的异常远比纤颤、正尖波检出率高 ,且随病情的加重改变愈加明显 ;F波与 H反射异常率不高 ,提示很少累及神经根 ;SEP的异常率高达 6 0 .8% ,同时说明该组患者伴有中枢神经的损害。结论 神经电生理检测可以用来观察燃煤污染型慢性砷中毒患者的神经系统损害程度、病程、范围 ,亦是该病的早期检查手段之一
Objective To evaluate the neurological damage in patients with chronic arsenic poisoning caused by coal combustion. Methods Electromyography, motor nerve conduction velocity (MCV), sensory nerve conduction velocity (SCV), F wave, H reflex and somatosensory evoked potentials (SEP) were randomly detected in 51 patients. Results Sixty-six.7% of 12 muscular EMGs were dominated by polyphase irregular waves. Both MCV and SCV were slowed down, while SCV slowed down most significantly while the latency of MCV distal action potentials was significantly prolonged. The nerve conduction velocity (NCV) is much higher than that of fibrillation and positive spikes, and it is more obvious with the aggravation of the disease. The abnormal rate of F wave and H reflex is not high, suggesting that the nerve roots are rarely involved. The abnormal rate of SEP is as high as 6 0 .8%, at the same time that this group of patients with central nervous system damage. Conclusion The neuroelectrophysiological test can be used to observe the extent, duration and extent of neurological damage in patients with coal-burning chronic arsenic poisoning and is also one of the early means of examination of the disease