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患者、男,35岁,因患鼻窦炎,于1990年12月17日肌注卡那霉素50万 u 约0.5min 后突感胸闷、心慌、气短、头晕而晕倒。查体;面色苍白,四肢厥冷,轻度寒战,心率120次/min,呼吸32次/min,神志清楚,血压11.5/8kPa。即刻肌注副肾素0.8ml,吸氧,50%葡萄糖加地塞米松5mg 静脉注射、10min 后症状逐渐缓解,0.5h 后基本恢复正常。24h 内患者自觉乏力,头晕,经观察和对症治疗痊愈。患者既往有青霉素、链霉素过敏史。经查验,本次使用的卡那霉素无变色,变质现象,按无菌操作规程进行。上述反应经分析认为属卡那霉素过敏所致。卡那霉素临床毒副作用主要是:①对第八对脑(听)
Patients, male, 35 years old, suffering from sinusitis, on December 17, 1990 intramuscular kanamycin 500,000 u about 0.5min suddenly felt chest tightness, palpitation, shortness of breath, dizziness and fainting. Physical examination; pale, limbs Jueleng, mild chills, heart rate 120 beats / min, breathing 32 beats / min, conscious, blood pressure 11.5 / 8kPa. Immediate intramuscular injection of Vice Renin 0.8ml, oxygen, 50% glucose plus dexamethasone 5mg intravenously, 10min after the symptoms gradually eased, 0.5h after the basic return to normal. Patients within 24 hours of fatigue, dizziness, the observation and symptomatic treatment healed. Past history of patients with penicillin, streptomycin allergy history. After examination, the use of kanamycin no discoloration, deterioration, according to aseptic procedures. The above reaction was analyzed as kanamycin allergy. The clinical side effects of kanamycin are: ① on the eighth pair of brain (listen)