自1978年以来,我们采用环磷酰胺与莨菪碱联合应用治疗顽固性哮喘,取得了较好的效果。现将临床资料较完整的15例总结如下。 临床资料 一、病例选择 1.有支气管哮喘病史两年以上;2.发作期有典型的临床症状;3.发作期间使用各种药冶疗一月以上,排除其他诱因仍不能缓解或不能停药;4.排除其他疾病引起的哮喘。同期接诊的病人随机分为二组,观察组15例,对照组16例。 Since 1978, we have used cyclophosphamide and scopolamine in the treatment of intractable asthma, and achieved good results. Clinical information now more complete 15 cases are summarized below. Clinical data A case selection 1. Have a history of bronchial asthma more than two years; 2. The onset of a typical clinical symptoms; 3. Attack during the use of various drugs for more than a month, excluding other incentives still can not be relieved or can not stop ; 4 to rule out other diseases caused by asthma. Concurrent admissions of patients were randomly divided into two groups, the observation group of 15 cases, control group of 16 cases.