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新生儿指出生后一个月以内的婴儿。此时婴儿开始脱离母体,但由于机体发育的不成熟和适应能力的不完善,故生命特别脆弱。然而,临床上新生儿患病率较高,有些医师使用西药特别审慎,而习惯于应用被认为几无副作用的中药进行治疗。为此,笔者认为不宜使用内含苯甲醇附加剂的中药注射液,这是因为苯甲醇在体内氧化为苯甲酸,在肝中与甘氨酸结合生成马尿酸排除体外,上述反应系酰基结合,常需借助于酰基辅酶A合成酶和酰基转移酶的催化进行的,而新生儿未成熟的肝脏缺乏这些酶,故对苯甲醇代谢能力低,因
Newborns point out infants within one month after birth. At this point the baby began to leave the mother, but life is particularly vulnerable due to the immature body and immature adaptive capacity. However, the prevalence of clinically newborns is high, and some physicians are particularly cautious about using western medicine and instead are accustomed to using traditional Chinese medicines that are considered to have few side effects. For this reason, I think it is not appropriate to use traditional Chinese medicine injection containing benzyl alcohol additive injection, which is because benzyl alcohol in vivo oxidation of benzoic acid, glycine in the liver and generate hippuric acid exclusion in vitro, the reaction of acyl combination, often With the aid of acyl-CoA synthetase and acyltransferase catalysis, and neonatal immature liver lack of these enzymes, it has low ability to metabolize benzyl alcohol due to