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目的建立正常新生儿及6月~10岁儿童血清甘露聚糖凝集素(MBL)水平正常值参考范围。方法用ELISA方法检测262例新生儿脐血MBL水平及6月~10岁健康儿童血清MBL水平,比较不同地区、不同族别、不同性别新生儿、正常儿童血清MBL水平。结果新生儿脐血MBL值为(1.71±1.60)mg/L,6月~10岁正常儿童外周血MBL值为(3.09±1.58)mg/L,两者间差异有统计学意义(P<0.05),汉族及维族新生儿脐血MBL值比较差异无统计学意义(P>0.05);汉族与维族6月~10岁正常儿童血清MBL值比较差异无统计学意义(P>0.05);不同性别正常儿童血清MBL值比较,差异无统计学意义(P>0.05)。结论确立不同年龄段儿童血清MBL值对临床治疗将有很重要意义。
Objective To establish a reference range of normal serum MBL levels in normal newborns and children aged 6 months to 10 years. Methods Serum MBL levels were measured in 262 neonates with cord blood samples and serum MBL levels in healthy children aged 6 months to 10 years by ELISA. Serum MBL levels were compared between different genders, in different genders and in different sexes. Results The MBL of neonatal umbilical blood was (1.71 ± 1.60) mg / L and that of normal children from June to 10 was (3.09 ± 1.58) mg / L, the difference was statistically significant (P <0.05 ), There was no significant difference in the MBL value of cord blood among Han and Uighur newborns (P> 0.05). There was no significant difference in serum MBL between Han and Uighur children between June and 10 years (P> 0.05) There was no significant difference in serum MBL between normal children (P> 0.05). Conclusion Establishing serum MBL in children of different ages will be of great significance for clinical treatment.