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目的:探讨口腔卫生维护对2型糖尿病患者种植牙牙周情况和糖化血红蛋白的影响。方法:将113名种植牙患者分为三组,第一组38名,为未患糖尿病者,糖化血红蛋白值<6%;第二组36名,为2型糖尿病患者,糖化血红蛋白值在6.1%~8.0%之间;第三组39名,为2型糖尿病患者,糖化血红蛋白值在8.1%~10.0%之间。三组患者均种植牙后即刻负重,在术后每6个月进行牙周/种植体周洁治;分别在术后6个月、1年和2年行龈沟出血指数(sulcus bleeding index,SBI)、探诊深度(probing depth,PD)和骨丧失深度(the distance from the shoulder of the implant to the bottom of the bony defect,DSB)检测。结果:第一、二、三组术前的平均糖化血红蛋白值分别为4.85%、6.88%和8.64%;在第一组,术前、术后6个月、术后1年和2年的糖化血红蛋白值之间的变化无统计学差异(P>0.05);在第二组和第三组,术后2年和术后6个月之间的糖化血红蛋白值显著下降(P<0.01);在术后6个月,第一组的SBI、PD和DSB低于第三组,差异有统计学意义(P<0.01);在术后1年和2年,观察二组的DSB均显著性高于第三组(P<0.01);第三组的SBI和PD在术后2年时较术后6个月时显著下降(P<0.01)。结论:口腔卫生维护可降低2型糖尿病人种植牙后的糖化血红蛋白值,同时也能缓解种植体周围的炎症症状。
Objective: To investigate the effects of oral hygiene maintenance on periodontal status and HbA1c in dental implants of type 2 diabetic patients. Methods: One hundred and thirty-one dental implant patients were divided into three groups, the first group consisted of 38 patients with no diabetes, the values of HbA1c <6%; the second group of 36 patients with type 2 diabetes, the HbA1c values were 6.1% ~ 8.0%; the third group of 39 patients with type 2 diabetes, glycated hemoglobin value between 8.1% to 10.0%. The three groups of patients were immediately loaded with dental implants, and the periodontal / implants were implanted at 6 months postoperatively. The sulcus bleeding index (SBI) were measured at 6 months, 1 year and 2 years after operation. , Probing depth (PD) and the distance from the shoulder of the implant to the bottom of the bony defect (DSB). Results: The preoperative average values of HbA1c in the first, second and third groups were 4.85%, 6.88% and 8.64% respectively. In the first group, preoperative and postoperative 6 months, postoperative 1 and 2 years of saccharification There was no significant difference between the hemoglobin values (P> 0.05). In the second and third groups, the values of HbA1c decreased significantly between the two years after operation and the six months after operation (P <0.01) Six months after operation, the SBI, PD and DSB in the first group were lower than those in the third group (P <0.01). At 1 year and 2 years after operation, the DSB of the two groups were significantly higher In the third group (P <0.01). SBI and PD in the third group decreased significantly at 2 years after surgery compared with 6 months after operation (P <0.01). Conclusion: Oral hygiene maintenance can reduce the value of HbA1c in dental implants of type 2 diabetics and relieve the inflammatory symptoms around implants.