Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids

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Dear Editor,rnThe emerging pandemic of coronavirus,SARS-CoV-2 (previously named 2019-nCoV),has posed significant threats to global public health (Wu et al.,2020).The dominant symptoms of coronavirus disease 2019 (COVID-19) are fever and cough (Chen et al.,2020;Huang et al.,2020).However,a proportion of patients showed multi-organ damage and dysfunction (Chen et al.,2020;Huang et al.,2020;Zhu et al.,2020).
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