论文部分内容阅读
心肌缺血预适应是指心脏能从短暂缺血中快速适应,减轻随后较长时间缺血所致的致命性心肌损害。为探讨心肌缺血预适应对急性心肌梗塞(AMI)的梗塞面积及近期预后的影响,本文对116例AMI患者临床资料做回顾分析如下。1 对象与方法1.1 对象 116例AMI患者均系本院1993年3月至1997年10月住院治疗者,有典型临床表现、心电图动态变化及心肌酶显著升高,均符合1979年WHO)制汀的AMI标准。根据AMI前72小时内有无心肌缺血心绞痛,将病例分为缺血预适应组(A组,65例)和无缺血预适应组(B组,51例),两组的性别、年龄及冠心病危险因素均相似(P>0.05,见表1)。两组均采用常规治疗方法,未接受溶栓治疗。
Myocardial ischemic preconditioning refers to the rapid adaptation of the heart from transient ischemia, which reduces fatal myocardial damage resulting from prolonged ischemia. To investigate the effect of myocardial ischemic preconditioning on infarct size and short-term prognosis of acute myocardial infarction (AMI), the clinical data of 116 patients with AMI were retrospectively analyzed as follows. 1 Subjects and Methods 1.1 Object 116 cases of AMI patients were hospitalized in our hospital from March 1993 to October 1997, typical clinical manifestations, ECG changes and myocardial enzymes were significantly elevated, are consistent with the 1979 WHO) AMI standard. The patients were divided into ischemic preconditioning group (group A, 65 cases) and ischemic preconditioning group (group B, n = 51) according to the presence or absence of myocardial ischemia and angina within 72 hours before AMI. The gender, age And coronary heart disease risk factors were similar (P> 0.05, Table 1). Both groups were treated by conventional treatment, did not receive thrombolytic therapy.