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目的:研究欣普贝生在延期妊娠促宫颈成熟中的临床应用效果。方法:使用对照观察的方式,选取27例孕40到41周的具有引产特点的足月待产产妇当作观察组,在阴道内应用欣普贝生栓剂,这些产妇无严重的合并症并发症、胎位正常、单胎、没有阴道分娩禁忌。选取条件相同的孕妇27例的当作对照组,通过静脉滴注小剂量的缩宫素,对比观察组和对照组的新生儿影响、分娩情况以及宫颈Bishop评分。结果:对照组在用药之后宫颈Bishop评分显著低于观察组。观察组促宫颈成熟时间12小时,显著高于对照组,P<0.01。观察组的临产时间12小时显著高于对照组。两组产妇的产后出血量对比以及两组产妇新生儿的影响差异无统计学意义。出现的主要不良反应时宫缩过度,将其取出后显著好转。结论:欣普贝生属于安全性高、效果良好的促宫颈成熟药物,在引产中具有较大应用价值。
OBJECTIVE: To study the clinical effect of Hinbu Beishen in promoting cervical ripening in delayed pregnancy. Methods: The 27 pregnant women with gestational age of 40 to 41 weeks pregnant with full-term pregnant women were selected as the observation group by the way of contrast observation. The patients were treated with Hinbbeli suppository within the vagina. These women had no severe complication complications, Normal fetal position, single child, no vaginal birth taboo. Twenty-seven pregnant women of the same condition were chosen as the control group, and the effects of newborns, delivery and cervix Bishop score were compared by intravenous infusion of low-dose oxytocin. Results: The cervical Bishop score of the control group after treatment was significantly lower than that of the observation group. Observation of cervical ripening time 12 hours, significantly higher than the control group, P <0.01. Observation group of 12 hours of labor was significantly higher than the control group. The two groups of maternal postpartum hemorrhage comparison and the impact of the two groups of maternal newborns no significant difference. The main adverse reactions occurred when uterine excess, after taking it significantly improved. Conclusion: The drug is a safe and well-developed cervical ripening drug, which has great value in the induction of labor.