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目的:探讨经尿道膀胱肿瘤电切术(TURBT)联合丝裂霉素膀胱灌注治疗非浸润性膀胱尿路上皮癌的临床疗效及并发症和不良反应。方法:采用TURBT联合丝裂霉素膀胱灌注治疗70例非浸润性膀胱尿路上皮癌患者,回顾性分析患者的临床病理资料。结果:一次性切除68例,分期切除2例,手术时间30分钟~60分钟,平均住院10天,无手术并发症发生。术后病理诊断移行细胞癌64例,乳头状癌6例,术后随访3个月~2年,8例复发,复发率为11.4%(8/70)。结论:TURBT联合丝裂霉素膀胱灌注治疗非浸润性膀胱尿路上皮癌效果良好,并发症少。
Objective: To investigate the clinical efficacy, complications and adverse reactions of transurethral resection of bladder tumor (TURBT) combined with intravesical instillation of mitomycin in the treatment of non-invasive bladder urothelial carcinoma. Methods: TURBT combined with mitomycin in bladder irrigation in 70 patients with non-invasive bladder urothelial carcinoma patients were retrospectively analyzed the clinical and pathological data. Results: A total of 68 cases were resected at one time and 2 cases were staged. The operation time was 30 minutes to 60 minutes. The average hospitalization was 10 days. No operative complications occurred. Postoperative pathological diagnosis of 64 cases of transitional cell carcinoma, papillary carcinoma in 6 cases, followed up for 3 months to 2 years, 8 cases of recurrence, the recurrence rate was 11.4% (8/70). Conclusion: TURBT combined with mitomycin intravesical instillation is effective in treating non-invasive bladder urothelial carcinoma with fewer complications.