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目的调查一起幼儿园胃肠炎聚集性疫情。方法拟定病例定义搜索病例并作描述性分析;采集病例的肛拭子、呕吐物标本、食堂留样食物和班级饮水及桌面涂抹标本作病原学检测;同时采用病例对照研究分析病因。结果共搜索到病例11例,均有呕吐症状,部分伴有腹痛、腹泻和恶心等症状,所有病例均为小三班儿童,班级罹患率为36.67%。采集患儿5份肛拭子和1份呕吐物,经PCR检测,2份肛拭子和1份呕吐物诺如病毒GⅡ型阳性。病例对照研究显示与患病儿童有肢体接触为发病危险因素,其OR值(95%CI)为7.47(1.10~58.81)。结论本次疫情为一起由诺如病毒引起的胃肠炎聚集性疫情,危险因素为接触传播。
Objective To investigate a kindergarten gastroenteritis aggregation epidemic. Methods The cases were defined and descriptively analyzed. Anxious swabs, vomit samples, canteens food samples, class drinking water and desktop smear samples were collected for etiological detection. Case-control studies were also performed to analyze the etiology. Results A total of 11 cases were found, all of them had vomiting symptoms. Some of them were accompanied by abdominal pain, diarrhea and nausea. All the cases were small three classes with an attack rate of 36.67%. Collect 5 pieces of anal swabs and 1 piece of vomitus in children. After PCR detection, 2 pieces of anal swabs and 1 piece of vomitus Norovirus positive for GⅡ. Case-control studies showed that physical contact with affected children was a risk factor for morbidity, with an OR (95% CI) of 7.47 (1.10-58.81). Conclusion The outbreak is a gathering epidemic of gastroenteritis caused by norovirus and the risk factor is contact transmission.