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目的探讨心肌酶在小儿重度颅脑损伤检测意义。方法选择我院重度颅脑损伤患儿40例。所选患儿均在入院后第1天、第3天和第7天抽取静脉血进行心肌酶谱检测。根据格拉斯哥预后评分(GOS)把40例患儿分为三组,A组,包括预后良好及预后中残,共24例。B组,包括预后重残和植物生存,共10例。C组,包括死亡病例,共6例。结果 C组肌酸激酶、肌酸激酶同工酶、谷草转氨酶水平分别与B组和A组比较,差异有统计学意义(P<0.05);B组肌酸激酶、肌酸激酶同工酶、谷草转氨酶水平分别与A组比较,差异有统计学意义(P<0.05)。结论心肌酶谱水平越高预示着重度颅脑损伤患儿预后不良,监测心肌酶改变情况,有助于判定此类患儿预后。
Objective To investigate the significance of myocardial enzymes in severe craniocerebral injury in children. Methods Forty children with severe craniocerebral injury in our hospital were selected. Selected children were admitted to the first day, 3 days and 7 days after the venous blood was drawn for myocardial enzyme detection. According to the Glasgow Outcome Scale (GOS), 40 children were divided into three groups, Group A, including a good prognosis and a residual disability, a total of 24 cases. B group, including the prognosis of severe disability and plant survival, a total of 10 cases. C group, including deaths, a total of 6 cases. Results The levels of creatine kinase, creatine kinase and aspartate aminotransferase in group C were significantly lower than those in group B and group A, respectively (P <0.05). The creatine kinase, creatine kinase isoenzyme, Aspartate aminotransferase levels were compared with the A group, the difference was statistically significant (P <0.05). Conclusions The higher level of myocardial enzymes indicates the poor prognosis of children with severe craniocerebral injury and the monitoring of myocardial enzymes, which may help to determine the prognosis of these children.