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[目的]检测儿童接种新甲型H1N1流感疫苗后远期血清抗体水平,评价其体液免疫持久性。[方法]用ELISA法对2009年12月—2010年1月新甲型H1N1流感疫苗接种儿童进行新甲型H1N1流感抗体检测。[结果]2013年12月21日采集样本,32名儿童血清新甲型H1N1流感抗体平均水平仅为69.75 ng/L,阳性保护率为15.63%,男女性别间及7~8、9~10岁年龄组间抗体阳性率差异均无统计学意义(P>0.05)。[结论]新甲型H1N1流感疫苗远期体液免疫保护较差,7~10岁儿童如需取得较好抗体保护,需再次接种。
[Objective] To detect the level of long-term serum antibodies in children after being vaccinated with the new influenza A (H1N1) virus and to evaluate their humoral immunity persistence. [Method] The ELISA method was used to detect the new type A H1N1 influenza virus in children receiving new influenza A (H1N1) vaccine from December 2009 to January 2010. [Results] The average serum anti-H1N1 antibody levels of 32 children collected on December 21, 2013 were only 69.75 ng / L, the positive protection rate was 15.63%, between men and women and between 7 to 8 and 9 to 10 years old There was no significant difference in antibody positive rate between the age groups (P> 0.05). [Conclusion] The long-term protection against humoral immunity of the new influenza A (H1N1) influenza vaccine is poor. Children aged 7 to 10 years need better vaccination to be vaccinated again.