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目的 :探讨替硝唑注射液治疗妇科厌氧菌感染的临床疗效、副作用及应用前景。方法 :10 4例诊断为厌氧菌感染患者分为两组 :替硝唑组 5 6例 ,甲硝唑组 48例 ,治疗前行厌氧菌培养并观察临床效果、细菌阴转情况及副反应。结果 :治疗组有效率 98.2 % ,对照组 85 .4% (P <0 .0 1) ;细菌阴转率分别为 93.9%和 75 .0 % (P <0 .0 5 ) ,胃肠道反应率分别为 10 .7%和 6 8.8%(P <0 .0 0 5 )。结论 :替硝唑注射液治疗妇科领域厌氧菌感染优于甲硝唑液 ,可应用于产褥期感染。
Objective: To investigate the clinical efficacy, side effects and application prospects of tinidazole injection in the treatment of gynecological anaerobic infections. Methods: A total of 104 patients diagnosed as anaerobic infections were divided into two groups: 56 patients in the tinidazole group and 48 patients in the metronidazole group. Anaerobic bacteria were cultured before treatment and the clinical effect, reaction. Results: The effective rate was 98.2% in the treatment group and 85.4% in the control group (P <0.01). The negative rates of bacteria were 93.9% and 75.0% (P <0.05) respectively. The gastrointestinal reaction Rates were 10.7% and 6 8.8%, respectively (P <0.05). Conclusion: Tinidazole injection is superior to metronidazole in the treatment of anaerobic infections in gynecology and may be used in puerperium infection.