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急性早幼粒细胞白血病(APL)是急件粒细胞白血病(AML)的一种亚型,具有明显的出血倾向、低纤维蛋白原血症和独特的形态学特征。有关APL的血象及骨髓象观察,国内外已有报道。现将我们近期内收治APL12例的血象及骨髓象分析于下。材料和方法本组病例骨髓穿刺均于治疗前施行,标本采自髂骨后上棘。末梢血液检查均采自指尖毛细血管。全部标本用瑞氏染色。血片用油镜进行200个白细胞分类并注意成熟红细胞的大小、形态、染色和血小板量与质的情况。骨髓象涂片的观察项目有:骨髓有核细胞的增生程度;计数全片巨核细胞数;用油镜行500个有核细胞分类;注意其他细胞质与量的情况。
Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML) with significant bleeding tendency, hypofibrinogenemia and unique morphological characteristics. APL blood and bone marrow observed, both at home and abroad have been reported. Now we have APL12 cases of recent treatment of blood and bone marrow analysis in the next. Materials and methods of bone marrow puncture in this group were performed before treatment, specimens collected from the posterior superior iliac spine. Peripheral blood tests were taken from fingertips capillaries. Watson stain all specimens. Blood film using an oil microscope for the classification of 200 white blood cells and pay attention to the size of mature erythrocytes, morphology, staining and platelet quality and quality. Bone marrow smear observation items are: degree of proliferation of bone marrow nucleated cells; count the number of megakaryocytes; using oil microscopy of 500 nucleated cells; pay attention to other cytoplasmic and quantitative conditions.