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目的探讨P300亚成份P3a波的神经起源。方法兔头颅表面选取多个有代表性的点为探测点,所有记录点均在大脑半球两侧对称部位不同深度先后测试ERPs,并观察Pu波的空间分布特点,推测出P3a 波的可能起源部位。结果头颅各记录点不同深度的P3a波潜伏期无显著性差异(P >0.05)。acg5点的颅骨下P3a波极性翻转率最高(P< 0.05),且acg5及毗邻点acg4未翻转的P3a波都具有电位梯度(7mm处波幅最大),在其附近的F3(F4)、acg3及acg7等点颅骨P3a波有中等度的电位梯度,而其它点颅内P3a波的电位梯度变化相对较小或无规律。结论兔acg5与acg4两点颅骨下6~7mm附近区域(Brodmann25、32区)可能是兔P3a波的起源。
Objective To investigate the neural origin of P300 subunit P3a wave. Methods A number of representative points were chosen as probing points on the skull surface of the rabbit. ERPs were tested at different depths on both sides of hemispheres at all depths. The spatial distribution of Pu waves was also observed. The possible origin of P3a . Results There was no significant difference in the P3a wave latency at different depths at all recording sites (P> 0.05). (P <0.05), and acg5 and P3a wave of the adjacent point acg4 did not turn over had a potential gradient (amplitude was the largest at 7mm), F3 (F4), acg3 And acg7 point skull P3a wave has a moderate potential gradient, and other points P3a wave potential gradient changes are relatively small or irregular. Conclusion Rabbit acg5 and acg4 two cranial skull 6 ~ 7mm near the area (Brodmann25,32 area) may be the origin of P3a wave in rabbits.