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已正式批准使用的乙型肝炎(乙肝)疫苗包括早期的血源疫苗和目前普遍使用的重组疫苗,按标准方案实施一个免疫程序后确有一定比例的接种者乙肝表面抗体(抗-HBs)滴度不能达到保护水平即10 U／L,在健康人群中该比例波动在2％～ 15％之间。这些无应答者对乙肝病毒(HBV)仍然易感,一旦感染仍可发病或成为病毒携带者。对其原因及机制的研究已取
Hepatitis B (hepatitis B) vaccines that have been officially approved include early blood-borne vaccines and recombinant vaccines currently in widespread use. A certain percentage of vaccinated hepatitis B surface antibodies (anti-HBs) are present after an immunization program is administered according to the standard protocol Degree can not reach the level of protection that is 10 U / L, the proportion of fluctuations in the healthy population between 2% to 15%. These non-responders are still susceptible to hepatitis B virus (HBV) and can still develop or become virus carriers once infected. The reason and mechanism of the research has been taken