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通过研究丙型肝炎病毒(HCV)的核心蛋白与p53、Bcl-2在丙型肝炎中的表达,探讨HCV核心蛋白(HCV-C)对p53、BCl-2蛋白表达的可能作用及其影响肝细胞生长和分子表达,为研究HCV-C对慢性肝疾病和肝细胞癌变的发生发展及其分子作用机制提供参考。
To investigate the possible role of HCV core protein (HCV-C) in the expression of p53 and BCl-2 protein and its effect on the expression of hepatitis B virus (HCV) Cell growth and molecular expression, provide a reference for the study of HCV-C on the occurrence and development of chronic liver disease and hepatocellular carcinoma and its molecular mechanism.