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目的研究男性代谢综合征患者踝臂指数(ABI)与全因及心血管疾病病死率的关系。方法收集上海、北京地区男性代谢综合征患者1224例,分为低 ABI 组(ABI≤0.9)与正常 ABI 组(ABI 0.9～1.4),测量其完整的基线资料,并进行随访调查。结果经过(13.2±2.7)个月,共死亡89例,其中40例为心血管疾病死亡。随着 ABI 值的降低,人群全因及心血管疾病病死率有显著升高趋势,Cox 回归分析显示ABI≤0.9与两者显著相关。低 ABI 组的生存率显著低于正常 ABI 组。结论低 ABI 是男性代谢综合征患者发生全因及心血管疾病死亡的独立性危险因素,在该人群中早期运用ABI 测定对心血管疾病死亡具有预测价值。
Objective To investigate the relationship between ankle-brachial index (ABI) and all-cause and cardiovascular mortality in men with metabolic syndrome. Methods A total of 1224 patients with metabolic syndrome in Shanghai and Beijing were collected and divided into low ABI group (ABI≤0.9) and normal ABI group (ABI 0.9 ~ 1.4). The complete baseline data were measured and followed up. Results (13.2 ± 2.7) months, a total of 89 deaths, of which 40 were cardiovascular deaths. With the decrease of ABI value, the mortality rate of all-cause and cardiovascular disease in the population increased significantly. Cox regression analysis showed that ABI≤0.9 was significantly correlated with both. The survival rates in the low ABI group were significantly lower than those in the normal ABI group. Conclusions Low ABI is an independent risk factor for all-cause and cardiovascular death in patients with metabolic syndrome. Prediction of death from cardiovascular diseases by ABI in early stage of this population is of great value.