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短串联重复序列(STR)是鉴定亲缘关系的重要技术手段之一。本文对中国山东地区25名确定亲缘关系的四代家系成员的18个基因座进行STR分型检测,发现vWA基因座连续两代发生基因突变,并对该基因座突变现象进行分析探讨。
Short tandem repeats (STRs) are one of the important techniques for identifying kinship. In this study, STR loci were detected in 18 loci of 25 identified fourth-generation family members in Shandong Province, China. Mutations were detected in two generations of vWA loci, and the mutation of this locus was analyzed.