论文部分内容阅读
多年来我厂生产的肠溶衣片如红霉素片、麦迪霉素片、呋喃(口旦)啶片等一直采用虫胶作肠溶衣材料(pH>6.4可溶),由于中国药典(1985版)规定了新的人工肠液,即pH值由7.3变为6.8,故虫胶在人工肠液中的可溶性降低了。因此,按原虫胶工艺生产很不稳定,产品在人工肠液中不崩解的情况时有发生。针对上述情况,我们对肠溶衣片的包衣材料和工艺
Over the years I plant the enteric-coated tablets such as erythromycin tablets, midecamycin tablets, furan (dandan) and other films have been used shellac for enteric coating materials (pH> 6.4 soluble), due to the Chinese Pharmacopoeia ( 1985 version) provides a new artificial intestinal juice, that is, the pH value of 7.3 to 6.8, so the shellac in the artificial intestinal fluid solubility reduced. Therefore, according to the production of raw shellac is very unstable, the product does not collapse in the artificial intestinal fluid has occurred from time to time. In view of the above situation, we enteric coated tablets coating materials and processes