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酒精滥用及依赖是不容忽视的医学社会学问题。酒精依赖的机制尚未明确，兴奋性递质谷氨酸及其受体与之关系较为密切。酒精依赖还与中枢的奖赏系统有关，该系统中的腹侧被盖区(ventral tegument area ,VTA)和伏核(nucleus accumbens ,NAcc)是酒精依赖引起奖赏效应的最后通路[1]
Alcohol abuse and dependence can not be ignored in medical sociology. The mechanism of alcohol dependence is not yet clear, and excitatory neurotransmitter glutamate and its receptor are closely related. Alcohol dependence is also linked to a central reward system in which the ventral tegument area (VTA) and nucleus accumbens (NAcc) are the last routes of reward-inducing effects of alcohol dependence [1]