论文部分内容阅读
目的 应用PTC针脐带穿刺取胎儿血进行产前诊断 ,评价其安全性及准确性 ,探索穿刺技巧。方法 用PTC穿刺针在超声引导下对 49例经遗传咨询筛选符合宫内诊断指征者进行了 5 1次脐带穿刺术。结果 穿刺成功率 94 1% (4 8/ 5 1) ,最终取血成功率为 98 0 % (4 8/ 49)。发现染色体平衡易位 3例 ,2 1三体 1例 ,甲型血友病 1例 ,宫内CMV感染伴胎儿异常 1例 ,亲子鉴定非丈夫血缘 1例。结论 使用PTC穿刺针进行脐带穿刺有较高的准确性及成功率 ,是较为有效的产前诊断方法
Objective To apply PTC needle umbilical cord puncture fetus fetus blood for prenatal diagnosis, evaluate its safety and accuracy, to explore the puncture skills. Methods Fifty-nine umbilical cord punctures were performed under the guidance of ultrasound guided by PTC puncture needle in 49 cases who were consulted to screen for intrauterine diagnosis by genetic counseling. Results The success rate of puncture was 94 1% (48/51), and the final success rate of blood collection was 98 0% (48/49). Three cases of chromosomal equilibrium translocation, one case of trisomy 21, one case of hemophilia A, one case of intrauterine CMV infection with abnormal fetus and one case of non-husband paternity test were identified. Conclusion The use of PTC puncture needle for umbilical cord puncture has a higher accuracy and success rate, which is a more effective prenatal diagnosis method