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作者报告了Virginia医学院1969.1～1975.12收治的248例能手术切除,首次治疗的口腔、口咽和下咽ⅡⅢⅣ期鳞癌的临床研究结果。全部病例于收治时,根据原发部位及TNM分期随机分入术前放疗或单一手术组。手术方式为原发灶切除加单或双侧颈清扫术。放疗技术为Co~(60)放射源双侧对穿野,从颅底到锁骨,包原发灶、咽后淋巴结及颈淋巴结区,以中线为深度中心。每次照左右两野,总量DT1400rad,于术前24小时和48小时两次给完。两组病例的年龄,性别,病期、原发部位、手术标本病理证实的淋巴结转移率及行双侧颈清扫术的病例数大致相同。全部病例均随访了4～9年。作者从四
The authors report the results of a clinical study of 248 squamous cell carcinomas of the mouth, oropharynx, and hypopharynx that were treated for surgery and for the first time at the Virginia Medical School from 1969.1 to 1975.12. All patients were randomly assigned to preoperative radiotherapy or single surgery group according to the primary site and TNM stage at admission. The surgical approach was primary resection plus bilateral or bilateral neck dissection. Radiotherapy techniques were Co~(60) radiation source bilaterally, field from skull base to clavicle, primary foci, retropharyngeal lymph nodes, and cervical lymph nodes, with the midline as the depth center. Each time the left and right sides were photographed, the total amount of DT1400rad was given twice at 24 hours and 48 hours before surgery. The age, sex, stage of disease, primary site, pathologically confirmed lymph node metastasis rate of the two groups and the number of bilateral neck dissections were approximately the same. All cases were followed up for 4 to 9 years. Author from four