苗勒氏恶性混合瘤少见,但病理表现特殊,恶性度高,预后差。本文报告4例,并参考文献,对有关问题加以讨论。例1 70岁,绝经20年。阴道流血溢液伴下腹痛两月余。妇科检查:宫口开5厘米,颈管内可触及5×4×3厘米大的息肉状肿块。子宫增大,如9周妊娠。临床诊断:子宫粘膜下肌瘤恶变。行全子宫及双侧附件切除,术后放疗。1年后死亡。大体检查:子宫底有一4 Miao Le’s malignant mixed tumor rare, but the special pathology, high malignant, poor prognosis. This article reports 4 cases, and references, to discuss the issues. Example 1 70 years old, menopause 20 years. Vaginal bleeding with abdominal pain more than two months. Gynecological examination: cervix open 5 cm, neck tube can reach 5 × 4 × 3 cm large polypoid mass. Uterus increases, such as 9 weeks of pregnancy. Clinical diagnosis: malignant submucosal fibroids. Line of hysterectomy and bilateral attachment resection, postoperative radiotherapy. 1 year after death. General examination: a 4 at the end of the uterus