设计合成了对 (间、邻 )苯二酚二 ( 4 氯 2 羟基苯基 )醚 ( 4a～ 4c)及对 (间、邻 )苯二酚二 ( 4 氯 5 溴 2 羟基苯基 )醚( 5a～ 5c)共 6个卤代羟基三苯醚类化合物 ,其结构均经1HNMR ,IR ,MS和元素分析证实 ,并且对其抑菌活性进行了初步测试 .结果表明 :此类化合物大多在低浓度下对大肠杆菌、金黄色葡萄球菌、白色念珠菌、白色葡萄球菌、变形杆菌、卡他双球菌、青枯假单胞菌等具有良好的抗菌活性 In this paper, a series of methods were designed and synthesized for the synthesis of bis (4-chloro-2-hydroxyphenyl) ether (4a ~ 4c) 5a ~ 5c) were synthesized and their structures were confirmed by 1HNMR, IR, MS and elemental analysis, and their antibacterial activities were tested.The results showed that most of these compounds were in the low Concentration of Escherichia coli, Staphylococcus aureus, Candida albicans, Staphylococcus aureus, Proteus, Proteus catarrhalis, Pseudomonas solanacearum has good antibacterial activity