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目的探讨阿卡波糖对社区糖尿病的治疗效果及安全性。方法选取洪塘街道社区卫生服务中心2015年3—7月收治的糖尿病患者100例,将其随机分为A组(阿卡波糖治疗)和B组(二甲双胍治疗),各50例。比较两组患者的治疗效果及安全性。结果治疗前两组患者空腹血糖、餐后2h血糖及糖化血红蛋白(Hb A1c)比较,差异无统计学意义(P>0.05)。治疗后两组患者空腹血糖、餐后2h血糖及Hb A1c均低于治疗前,差异有统计学意义(P<0.05);且A组空腹血糖、餐后2h血糖及Hb A1c均低于B组,差异有统计学意义(P<0.05)。A组治疗总有效率高于B组,差异有统计学意义(P<0.05)。两组不良反应发生情况比较,差异无统计学意义(P>0.05)。结论阿卡波糖治疗社区糖尿病患者的效果显著,且安全性高,可作为首选治疗方法并进行推广。
Objective To investigate the therapeutic effect and safety of acarbose on community diabetes mellitus. Methods 100 cases of diabetic patients treated in Community Health Center of Hongtang Sub-district from March to July in 2015 were randomly divided into group A (acarbose treatment) and group B (metformin treatment), 50 cases each. The therapeutic effect and safety of the two groups were compared. Results There was no significant difference in fasting blood glucose, 2h postprandial blood glucose and Hb A1c between the two groups before treatment (P> 0.05). After treatment, fasting blood glucose, postprandial 2h blood glucose and Hb A1c in both groups were significantly lower than those before treatment (P <0.05); and fasting blood glucose, 2h postprandial blood glucose and Hb A1c in group A were lower than those in group B , The difference was statistically significant (P <0.05). The total effective rate of treatment in group A was higher than that in group B, the difference was statistically significant (P <0.05). Adverse reactions between the two groups, the difference was not statistically significant (P> 0.05). Conclusion Acarbose treatment of community-based diabetes patients with significant effect, and high safety, as the preferred method of treatment and promotion.