脆性X综合症是近5～6年来新发现的一种性连锁遗传性疾病,是仅次于先天性愚型,较为多见的遗传性精神发育迟滞。其体征及染色体异常(Xq28)均有其特殊性,伴有中度或重度精神发育迟滞。言语发育缓慢,行为孤独,并有逐渐加重的趋势,易与其它儿童精神疾患相混淆。由于国内尚未报导,本文初步报告5例,以引起国内同道重视。 Fragile X syndrome is a newly discovered within the past 5 to 6 years, a genetic chain of genetic diseases, is second only to congenital stupid, more common hereditary mental retardation. Its signs and chromosomal abnormalities (Xq28) have their own particularity, with moderate or severe mental retardation. Slow speech development, behavior loneliness, and there is a gradual increase in the trend, easily confused with other child mental disorders. As China has not yet reported, this article preliminary report of 5 cases, in order to arouse the attention of domestic peers.