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目的应用超声心动图评价症状期酒精性心肌病(ACM)患者心脏结构及功能状态、戒酒及药物治疗效果。方法选取34例症状期ACM患者为观察组及34例查体正常者为对照组,行超声心动图检查,测量心脏结构及功能参数;观察组行戒酒及药物治疗,并对其中12例于治疗后随诊复查超声,比较治疗前后心脏结构功能的变化。结果与对照组比较,观察组心腔扩大、左室质量指数增加,左室收缩功能减低(P<0.01),二尖瓣舒张早期峰值流速(E)、舒张晚期峰值流速(A)均无统计学差异(P>0.05),而E/A>2者比例增多。与治疗前相比,治疗后左室舒张末径、左室质量指数减小(P<0.01,P<0.05),射血分数增加(P<0.01);而其余心腔大小、肺动脉收缩压的改变无统计学差异(P>0.05)。结论超声心动图可用于评价症状期ACM患者心脏结构和功能状态,是评价症状期ACM患者疗效和判断预后的无创性方法。
Objective To evaluate the cardiac structure and functional status, alcohol abstinence and drug treatment in patients with symptomatic alcoholic cardiomyopathy (ACM) by echocardiography. Methods 34 patients with ACM during symptom onset were selected as observation group and 34 normal controls as control group. Echocardiography was performed to measure cardiac structure and function parameters. The observation group was given alcohol and drug treatment, and 12 of them Follow-up ultrasound ultrasound treatment after treatment, changes in cardiac function before and after treatment. Results Compared with the control group, there was no statistical significance in the observation group in terms of enlarged left ventricle, increased left ventricular mass index, decreased left ventricular systolic function (P <0.01), mitral early peak diastolic velocity (E) and late diastolic peak velocity (A) (P> 0.05), while the proportion of E / A> 2 increased. Compared with those before treatment, left ventricular end diastolic diameter and left ventricular mass index decreased (P <0.01, P <0.05) and ejection fraction increased (P <0.01); while the rest of the heart cavity size, pulmonary artery systolic pressure No significant difference (P> 0.05). Conclusion Echocardiography can be used to evaluate the cardiac structure and functional status of patients with symptomatic ACM. It is a noninvasive method to evaluate the efficacy and prognosis of patients with ACM in symptomatic stage.