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目的:了解某院2007年乳房手术围手术期抗菌药使用情况,评价围手术期预防用药合理性。方法:收集2007年行乳房手术患者病历1154份,统计分析抗菌药应用情况。结果:乳房手术围手术期抗菌药使用率达100%,均为单联用药,头孢呋辛钠使用频率最高(75.30%),其次为头孢吡肟(17.85%);预防用药时机不合理率达98.7%,术后用药时间普遍偏长且用法用量不尽合理。结论:乳房手术围手术期抗菌药应用存在不合理现象,必须加强医生对抗菌药物合理使用知识的培训和建立有效的监督管理机制。
Objective: To understand the use of perioperative antibacterials during breast surgery in a hospital in 2007 to evaluate the rationality of perioperative prophylaxis. Methods: A total of 1154 medical records of patients undergoing breast surgery in 2007 were collected, and the application of antibacterials was statistically analyzed. Results: The use of antibacterials in perioperative period was 100%, all of them were single-drug combination. Cefuroxime sodium was the most frequently used (75.30%), followed by cefepime (17.85%). The irrational timing of preventive medication 98.7%, generally longer than the medication time and the amount of usage is not reasonable. Conclusion: There is an irrational use of antibacterials in perioperative period of breast surgery. It is necessary to strengthen the training of doctors on the rational use of antibacterials and to establish an effective supervision and management mechanism.