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1978年Goldenberg氏等应用~(131)碘标记抗癌胚抗原(CEA)抗体(放射免疫探测法)对人体CEA分泌性肿瘤的定位诊断首先获得成功。此后,相继应用~(131)碘标记抗甲胎蛋白(AFP)抗体、抗绒毛膜促性腺激素(HCG)抗体、以及抗前列腺酸性磷酸酶(PAP)抗体,分别作为AFP分泌性肿瘤、
In 1978, Goldenberg et al. applied the 131(131) iodine-labeled anti-carcinoembryonic antigen (CEA) antibody (radioimmunoassay) to localize the diagnosis of human CEA-secreting tumors first. Thereafter, ~(131)iodine-labeled anti-alpha-fetoprotein (AFP) antibodies, anti-chorionic gonadotropin (HCG) antibodies, and anti-prostatic acid phosphatase (PAP) antibodies were sequentially applied as AFP-secreting tumors, respectively.