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过氧化体增殖剂激活受体(PPARγ)与脂代谢、糖代谢和内皮细胞功能等心血管病危险因素密切相关。本文对PPARγ的生理病理功能,以及在心血管疾病中作用和相关的药物研究做一综述。
Peroxisome proliferator-activated receptor (PPARγ) is closely associated with cardiovascular risk factors such as lipid metabolism, glucose metabolism and endothelial cell function. This review summarizes the physiological and pathological functions of PPARγ and its role in cardiovascular diseases and related drug research.