食管癌是我国当今重点攻关的肿瘤之一。过去用动物诱发性肿瘤来寻找防治癌前病变及癌的药物，结果与人类肿瘤尚有一定的差距。so年代中期国内外开始应用体外培养的人食管癌细胞系接种于探鼠建立人食管癌保鼠移植瘤株，以研究人类食管癌的特征和筛选抗癌药物。但尚未直接应用人 Esophageal cancer is one of the most important tumors in our country today. In the past, animal-induced tumors were used to find drugs for preventing precancerous lesions and cancers, and there was still a certain gap between them and human tumors. In the middle of the mid-so, in vitro and in vivo human esophageal cancer cell lines were inoculated into a mouse to establish human esophageal cancer-rat transplant tumor lines to study the characteristics of human esophageal cancer and screen anticancer drugs. But not yet directly applied to people