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目的:探讨早产的主要影响因素及对其对母婴产生的危害,为制定预防措施提供依据。方法:采用病例对照研究的方法,回顾性分析2008年6～10月深圳市宝安区妇幼保健院318例早产孕妇的主要高危因素,将其分为早期早产组152例和中期早产组166例,对不同早产组的影响因素及其预后进行分析。结果:单因素分析得到8项早产危险因素,多因素Logistic回归分析发现影响早期早产的因素为早产史(OR=5.269)、胎膜早破(OR=4.522)、产检次数过少(OR=2.678);影响中期早产因素为宫内感染(OR=8.653)、早产史(OR=6.652)、中重度贫血(OR=3.089)。结论:早产史、胎膜早破、产前检查次数过少和中重度贫血是早产的主要危险因素,早期早产对产妇和新生儿的危害更为严重。
Objective: To explore the main influencing factors of premature delivery and its harm to mothers and infants, and provide the basis for making preventive measures. Methods: A case-control study was conducted to retrospectively analyze the main risk factors of 318 pregnant women with preterm birth in Shenzhen Maternal and Child Health Hospital from June to October in 2008, which were divided into 152 cases of early preterm birth group and 166 cases of midterm preterm birth group, The influencing factors and prognosis of different preterm birth groups were analyzed. Results: Eight risk factors for preterm birth were obtained by univariate analysis. Logistic regression analysis showed that the factors affecting early preterm birth were premature birth (OR = 5.269), premature rupture of membranes (OR = 4.522) (OR = 8.653), premature birth (OR = 6.652) and moderate to severe anemia (OR = 3.089). CONCLUSION: Premature birth, premature rupture of membranes, too few prenatal tests and moderate to severe anemia are the major risk factors for preterm birth. Early premature labor is more harmful to maternal and newborn infants.