乳腺癌作为危害妇女健康的主要恶性肿瘤 ,近年来发病率有上升的趋势。研究表明 ,乳腺癌大多为激素依赖性肿瘤 ,因此内分泌治疗就成为乳腺癌系统综合治疗的重要组成部分 ,在欧美国家内分泌治疗占乳腺癌药物治疗的 50 %。近年来随着基础研究及新型药物的开发和应用于临床 ,使乳腺 As a major malignant tumor that endangers women’s health, breast cancer has a rising trend in recent years. Research shows that most breast cancer hormone-dependent tumors, endocrine therapy has become an integral part of the comprehensive treatment of breast cancer system in the United States endocrine therapy accounts for 50% of breast cancer drug treatment. In recent years, with the basic research and development of new drugs and applied to the clinic, so that the breast