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应用聚合酶反应技术检测19例抗-HBC阳性,HBsAg阳性之母婴HBVDNA。结果显示,2/6HBc阳性母亲1/6抗-HBc阴性婴儿,1例抗HBc,抗-HBc,HBeAg阳性母亲的HB-VDNA阳性。证实了抗-HBc阳性,HBsAg阴性母亲不仅体内存在HBVDNA,而且经过子宫内胎盘传播导致了婴儿的宫内感染,说明不仅HBsAg阳性母亲,而且HBsAg阴性但抗-HBc阳性母亲同样可引起乙肝的宫内感染,对乙肝母婴传播的深入研究提供了资料。对今后研究乙肝病毒母婴垂直传播,不能仅限于HBsAg阳性母亲的人群机
Nineteen anti-HBC positive and HBsAg positive maternal-fetal HBV DNA were detected by polymerase chain reaction. The results showed that 1/6 anti-HBc negative 2 / 6HBc-positive mothers, and 1 positive HB-VDNA anti-HBc, anti-HBc, HBeAg-positive mothers. Confirmed the anti-HBc positive, HBsAg-negative mothers not only in vivo HBVDNA, but also intrauterine transmission of intrauterine infection led to intrauterine infection, indicating that not only HBsAg-positive mothers, but HBsAg-negative but anti-HBc-positive mothers can also cause hepatitis B Palace Infection, the hepatitis B mother to child transmission of in-depth study provided information. For the future study of hepatitis B virus vertical transmission of mother to child, can not be limited to HBsAg-positive mothers of the crowd